Day 2 :
Keynote Forum
Nicole Jane Brooke
Aged Care Consultancy, Australia
Keynote: Mindfulness in Care: Challenge the status quo by exploring a new way of thinking about your philosophy of care
Time : 09:30-10:15
Biography:
Nicole Jane Brooke is the Chief Executive Officer at Aged Care Consultancy Australia and has over 20 years of experience in aged care, retirement living and disability and holds a Clinical Associate Professor title with University of Tasmania in recognition of her international and national expertise in the sector. Nicole completed her PhD in aged care in 2010 at University of Technology, Sydney and resides on the the editorial board for the Journal of Palliative Care and Medicine. Nicole continues to develop innovative and leading edge support to organisations both in business optimisation and risk management, whilst specialisingrnin board and clinical governance, case management and leadership.
Abstract:
The philosophy of care is as central to organisational effectiveness, as are the values, vision and strategic plan. It creates a usable and practical foundation for all care interactions. To which one can enable effective communication, engaging synergies and evaluation of current and future needs across the organisation at every level. Mindfulness promotes the need to be present in the moment. The benefits of mindfulness include; improve quality of care and life, reduced anxiety, emotional stability, decreased incidence of depression, reduced stress, improved immune function, improved quality of sleep. Mindfulness is a state of being aware of what we are doing, how we are doing it, exploring more individual approaches for doing it, training our mind to be open to new opportunities and becoming more attuned to our own needs and the needs of our clients, team and partners. The foci of a core belief in mindfulness are the explicit need to find meaningful activities and develop relationships through autonomy, enablement, dignity, autonomy and privacy to name a few. The mind in mindfulness is about learning to mindful as opposed to mindlessness. Learning to be more effective, keeping an open mind, and actively participating in learning rather than just hearing or reading as we often become used to. Mindfulness speaks of the need to build a scaffold of knowledge and resourcing this adequately, rather than relying on a single point of contact or resource.
Keynote Forum
Win-Ping Deng
Taipei Medical University, Taiwan
Keynote: Recovery of Stem Cell Senescence By Platelet Rich Plasma To Delay Animal Aging
Time : 10:15-11:00
Biography:
Win-Ping Deng obtained his doctorate in cancer biology Harvard University in 1993. Wing-Ping then joined the postdoctoral training at Jac A. Nickoloff’s lab where he directed research of preferential repair of UV damage in highly transcribed DNA and research of mismatch repair of heteroduplex DNA intermediates of extrachromosomal recombination in mammalian cells. This led to the development of powerful genetic recombination analysis in mammalian cells. In 2000, he joined the faculty of the College of Oral Medicine at the Taipei Medical University where now he is the Distinguished University Professor and Deputy Dean at TMU. He pioneered a new research for combining stem cell and molecular imaging to study the cancer therapy or tissue regeneration.
Abstract:
Aging is a process related to loss of functional stem cell and then loss of tissue and organ regeneration potentials. Our previous result demonstrated that the life span of OVX-SAMP8 mice was significantly prolonged and similar to that of the congenic senescence resistant strain of mice after Platelet Rich Plasma (PRP)/embryonic fibroblast transplantation. This study is aimed to investigate the potential of PRP to recover cellular potential from senescence and then to delay animal aging. We first examined whether stem cells would be senescent in aged mice compared to young mice. Primary Adipose derived Stem Cells (ADSCs) and Bone Marrow derived Stem Cells (BMSCs) were harvested from young and aged mice and found that cell senescence was strongly correlated with animal aging. Subsequently, we demonstrated that PRP could recover cell potential from senescence, such as promote cell growth (cell proliferation and colony formation), increase osteogenesis, decrease adipogenesis, restore cell senescence related markers and resist the oxidative stress in stem cells from aged mice. The results also showed that PRP treatment in aged mice could delay mice, aging as indicated by survival, body weight and aging phenotypes (behavior and gross morphology) in term of recovering the cellular potential of their stem cells compared to the results on aged control mice. We concluded that PRP has potential to delay aging through the recovery of stem cell senescence and could be used as an alternative medicine for tissue regeneration and future rejuvenation
Keynote Forum
Kimberly A Greer
Texas A&M University, USA
Keynote: The dog as an ideal model for aging biology investigations
Time : 11:25-12:10
Biography:
Kimberly A. Greer graduated from Texas A and M University, College of Veterinary Medicine, in College Station, Texas with a specialty in Molecular and Developmental Genetics. After working on neural tube defect genetics, Kimberly moved her focus to canine genetics during her post-doctoral studies. She established her own laboratory at Indiana University east following extensive study at NIH and Eli Lilly. Here, she discovered the genotype responsible for necrotizing meningoencephalitis, an invariable fatal canine disease. Following a laboratory move to the North Dakota State University to establish a Genomics Research Institute, She returned to Texas where she currently continues research into the genetics of aging at Prairie View A&M University.
Abstract:
With many caveats to the traditional vertebrate species pertaining to biogerontology investigations, it has been suggested that a most informative model is the one which: • Examines closely related species, or various members of the same species with naturally occurring lifespan variation • Already has adequate medical procedures developed • Has a well annotated genome • Does not require artificial housing and can live in its natural environment while being investigated • Allows considerable information to be gathered within a relatively short period of time. The domestic dog unsurprisingly fits each criterion. The dog has already become a key model system in which to evaluate surgical techniques and novel medications because of the remarkable similarity between human and canine conditions, treatments and response to therapy. The dog naturally serves as a disease model for study, obviating the need to construct artificial genetically modified examples of disease. Just as the dog offers a natural model for human conditions and diseases, our laboratory has established the canine correlates of human aging, demonstrating the size-longevity correlation in the domestic dog. Further, we have evaluated genotype and longevity gene associations within and between the canines of variable lifespan. Our biochemical studies demonstrate correlations pertaining to the GH/IGF-1 pathway, outlining surprising differences amongst the four genders within our canine population of greater than 77 pure breeds and mixed breed animals. Currently, evaluation of primary fibroblasts delineates correlations of size, longevity and oxidative stress resistance as well as oxygen consumption rates within the species.rn