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4th Global Conference on Aging and Gerontology, will be organized around the theme “Palliative Care and Pain Management in Older Adults”
Aging 2025 is comprised of keynote and speakers sessions on latest cutting edge research designed to offer comprehensive global discussions that address current issues in Aging 2025
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Aging affects the whole brain functionality which leads to many psychiatric disorders which mainly includes dementia, cognitive impairment, depression, delirium etc. Mental disorders induce functional disability, disturb rehabilitation, burden the health system and impair life-quality of older patients and their relatives.the capacity for change and improvement. Factors like physical exercise, mental stimulation, social engagement, and a healthy lifestyle can significantly enhance neuroplasticity in older adults. Regular physical activity, especially aerobic exercise, promotes blood flow to the brain, stimulates neurogenesis, and boosts levels of brain-derived neurotrophic factor (BDNF), a protein that supports neuron growth. Likewise, engaging in cognitively challenging tasks, maintaining strong social connections, and adopting stress-reduction practices such as mindfulness can all contribute to sustaining or even enhancing neuroplasticity. These activities not only help maintain cognitive function but can also protect the brain against age-related decline and neurodegenerative diseases.
Palliative care is specific therapeutic administered to individuals with genuine ailments. It concentrates on giving help from the side effects and stretch of a genuine sickness. The objective is to enhance personal satisfaction for both the patient and the family. Palliative care is given by an exceptionally prepared and trained group of specialists, nurses, social labourers and different experts who cooperate with a patient's specialists to give a hospice palliative care. It is proper at any age and at any phase in a genuine ailment and can be furnished alongside healing treatment.It often involves a team of healthcare professionals, including doctors, nurses, social workers, and chaplains, who work together to support the patient and their family during this challenging time. One of the central principles of both palliative and end-of-life care is patient-centeredness, ensuring that care plans align with the patient’s values, preferences, and goals. This may involve discussions about advance directives, such as living wills or do-not-resuscitate orders, to make sure that the patient’s wishes are respected when they are no longer able to communicate them. Communication between the healthcare team, the patient, and the family is crucial to making informed decisions and providing personalized care that honors the patient's dignity
Geriatrics or Geriatric Medicine refers to the medical care for the elderly people whose age is above 65 years. The healthcare professionals who specialize in Geriatric are known as Geriatricians. Geriatricians are board-certified interns or family physicians who have additional training and certification in geriatrics. A focus on healthy aging, which involves staying active, maintaining a balanced diet, and managing stress, can help mitigate some of the challenges associated with getting older. Geriatrics is the branch of medicine that focuses on the healthcare of older adults. It encompasses a comprehensive approach to diagnosing, treating, and managing the unique health issues that arise in aging individuals. Geriatric care often involves addressing multiple chronic conditions simultaneously, managing medications carefully, and providing support for mental health, such as depression or cognitive decline. Geriatricians are specially trained to understand the complexities of aging and aim to enhance the quality of life for older adults by promoting independence, managing symptoms, and improving overall well-being. This field also emphasizes preventive care, encouraging early detection and intervention to help seniors maintain their health for as long as possible.
Retardation of Aging process is Anti - aging. One can play role in length and quality of your life. The latest emerging technologies in the arena of this field will be discussed. It has led to increase in the longevity and decrease in senescence. Anti- Aging products which mainly include supplements and hormone replacement are globally consumed.As cells divide, telomeres shorten, and this shortening is linked to cellular aging and the onset of age-related diseases. Scientists are investigating ways to extend telomeres or slow their shortening, with some promising therapies involving gene editing and the activation of telomerase, an enzyme that can rebuild telomeres. These breakthroughs offer potential for extending the lifespan of cells and possibly slowing down the aging process at the genetic level. Advancements in regenerative medicine also show great promise for anti-aging. Stem cell therapies, for example, aim to repair or replace damaged tissues and organs by harnessing the body's natural healing abilities. Stem cells have the potential to rejuvenate aging tissues, improve organ function, and even reverse some of the physical effects of aging. These therapies are still in the experimental phase, but they hold significant potential for improving health in older adults and extending longevity.
Life extension science is the concept of extending the human lifespan, both modestly – thru enhancements in medicine – or dramatically by way of growing the maximum lifespan. The potential to acquire such dramatic modifications, however, does not currently exist. Scientists believe that future breakthroughs in tissue rejuvenation, stem cells, regenerative medicinal drug, molecular repair, gene therapy, pharmaceuticals, and organ replacement (which includes with artificial organs or xenotransplantations) will ultimately allow human beings to have indefinite lifespans via whole rejuvenation to a healthy younger condition. Caloric restriction has been shown to extend lifespan in various organisms, and scientists are studying ways to activate these pathways without the need for drastic dietary changes. Stem cell research is another key component of life extension science, with the potential to regenerate aging tissues and organs. Stem cells can replace damaged cells, rejuvenate organs, and possibly reverse some of the effects of aging. The development of therapies to enhance the body's regenerative abilities through stem cell transplantation or the activation of endogenous stem cells is an exciting frontier in extending human healthspan. Additionally, researchers are exploring the role of telomeres, the protective caps at the ends of chromosomes, which shorten as we age. Strategies to preserve or lengthen telomeres could potentially slow the aging process at the cellular level, providing a powerful tool for extending life.
Senescence is defined as the period when synthetic (anabolic) biochemical process gives way to a degradative (catabolic) process. In general, it is the phenomenon of aging. It is the gradual deterioration of functional characteristics. It is the inevitable fate of all multicellular organisms with germ-soma separation, but it can be delayed. The pattern of Senescence can be Cellular Senescence, Tissue Senescence, Organ Senescence, Organism or Whole plant Senescence.The presence of these dysfunctional cells has also been linked to neurodegenerative diseases like Alzheimer's and Parkinson's, where they exacerbate cognitive decline. Senescence is not only a cellular process but also a broader biological phenomenon with implications for aging and disease. As research continues to uncover the mechanisms behind cellular senescence, it offers new opportunities for interventions that may help slow the aging process, improve health in older adults, and reduce the burden of age-related diseases.In tissues such as the skin, muscles, and blood vessels, senescent cells contribute to the decline in function and the development of age-related conditions. For example, in the skin, the accumulation of senescent cells can lead to wrinkles and reduced elasticity, while in the cardiovascular system, they contribute to arterial stiffness and the increased risk of heart disease
Aging care services are holistic, client-centred approach to caring for older adults or others facing on-going health challenges. Working with families, the expertise of Palliative Care provides the answers at a time of uncertainty. Their guidance leads families to the actions and decisions that ensure quality care and an optimal life for those they love, thus reducing worry, stress and time of work for family caregiver through individual health professionals.They work closely with the elderly individual, their family members, and healthcare providers to develop a tailored care plan. This plan may include a combination of medical care, home health services, physical therapy, social support, and assistance with activities of daily living (ADLs) such as bathing, dressing, and meal preparation. Care managers also assist with coordinating medical appointments, medication management, and advocating for the patient’s needs within the healthcare system. In addition to addressing the immediate healthcare needs of older adults, aging care management also focuses on long-term planning. This includes providing support for issues such as estate planning, financial management, and the exploration of housing options, such as aging in place at home, moving to an assisted living facility, or transitioning to skilled nursing care. A key goal is to ensure that older adults receive care in an environment where they feel comfortable and can maintain as much autonomy as possible.
Healthy food and healthy lifestyle leads to healthy aging. It helps in increasing the lifespan of humans. Intake of proper nutrients in diet helps us in attaining a better life at each stage of life. It has been found that people over the age of 65 years of age are either under-nourished or over- nourished..the aging process and enhancing longevity. A well-rounded diet for older adults should include a variety of nutrient-dense foods. For example, protein is essential for maintaining muscle mass, and older adults often require higher amounts to prevent sarcopenia (muscle loss). Foods like lean meats, fish, eggs, legumes, and dairy products are excellent sources of protein. Additionally, healthy fats, such as those found in nuts, seeds, avocados, and olive oil, support heart health and cognitive function. Whole grains, fruits, and vegetables provide fiber, vitamins, and minerals, all of which are vital for digestion, immune function, and preventing chronic illnesses. In particular, certain nutrients become even more important as individuals age. Calcium and vitamin D are critical for bone health, helping to prevent osteoporosis and fractures. Omega-3 fatty acids, found in fish like salmon and in supplements, support brain health and reduce inflammation, which is linked to many age-related diseases. Antioxidants, such as vitamins A, C, and E, protect cells from oxidative damage and support skin health, immune function, and cognitive well-being. Hydration is also essential for healthy aging, as the sense of thirst diminishes with age, increasing the risk of dehydration.
Clinical trials are one of the most advanced sciences in the domain of aging research. A clinical trial is a specific kind of research study performed in individuals which undergoes for assessing a restorative, surgical, or behavioural mediation. Most clinical trials test some other treatment, similar to another medication or eating routine or therapeutic gadget (for instance, a pacemaker) as a technique for treating a wellbeing issue. Other clinical trials test approaches to discover an ailment before there are even manifestations physically. A clinical trial may likewise take a gander at how to improve life for individuals living with an existence which involves undermining illness or a ceaseless wellbeing issue. Clinical trials sometimes concentrate on the part of parental figures or care groups. linical trials play a pivotal role in advancing our understanding of aging and developing new treatments to address the unique health challenges that come with it. As the global population continues to age, clinical trials focused on older adults have become increasingly important in the pursuit of improving health outcomes, extending lifespan
The transformative hypothesis of ageing offers a hypothetical structure that clarifies many, maybe most, perceptions and remains a noteworthy hypothetical point of interest in Gerontology. The hypothesis offers pieces of information with regards to the developmental systems and the occasions prompting the advancement of ageing, yet it doesn't offer an entire picture on the advancement of ageing across various species. Additionally, the transformative hypothesis of ageing can be destructive by forcing confinements on Ageing Studies. The way things are, the developmental hypothesis of ageing can't be securely used to make expectations on the biology of ageing. Transformative hypotheses of maturing are not prescient, they are spellbinding. For example, it has been opposed that non-ageing creatures, particularly those that increase size and productivity with age, might be supported by normal determination, accordingly negating the established developmental hypothesis of ageing. In species with a high infant mortality and long age times, a grown-up creature (adult animal) is valuable and worth protecting; if conceptive yield increases with age, characteristic determination will support conservation instead of quick generation.One important concept in this context is the role of longevity genes. In some organisms, such as certain species of fish or worms.
More than one in four American adults, according to a 2009 AARP survey, have become family caregivers to aging loved ones with chronic conditions. Of those caregivers, many spend, on an average, nearly 20 hours a week in addition to an outside job for caring about their elderly parents. Geriatric Care givers provide the required services for the elderly people.Home care services can be as simple as help with household tasks and companionship or as complex as medical care provided by nurses or physical therapists. This allows older adults to age in place, staying in a familiar environment while receiving the support they need. Home care services can also be adapted to meet a wide range of needs, from short-term assistance following surgery to long-term care for chronic conditions. For those who require more intensive care or cannot live independently at home, assisted living and nursing homes offer more structured environments. Assisted living facilities provide support with daily activities such as medication management, meal preparation, and personal care, while still allowing residents a certain degree of autonomy. Nursing homes, on the other hand, are typically for individuals who require around-the-clock medical care due to serious health conditions or advanced stages of aging. Both options offer specialized care designed to meet the evolving needs of older adults, and families can choose the level of care that best suits their loved ones.
The Dermatological states are intimately related to stress. Stress can influence, reveal or even exacerbate a number of skin disorders, including alopecia, seborrheic dermatitis, psoriasis, atopic dermatitis, pruritus, herpes, lichen planus, rosacea and urticarial. On the other hand, the skin disease itself could induce a secondary stress for the patient, influencing his or her quality of life.triggered by chronic stress, can lead to increased levels of pro-inflammatory cytokines, which contribute to skin conditions like eczema and rosacea. Stress can also cause a disruption in the gut-skin connection, where imbalances in the gut microbiome can manifest in skin issues. Conditions like acne and psoriasis are often linked to an imbalance in the gut, and stress can exacerbate this by negatively impacting digestion and gut health. The psychological effects of stress can also influence the skin, leading to habits such as picking or scratching, which can worsen conditions like acne or eczema. Additionally, stress can interfere with sleep, and poor sleep quality is known to have a detrimental effect on skin health. Lack of sleep can impair the skin’s ability to repair itself, leading to dullness, fine lines, and increased sensitivity. Over time, chronic stress and its impact on skin health can create a vicious cycle, where skin problems lead to more stress, which, in turn, worsens the skin condition.
As indicated by insights of the American Society for Aesthetic Plastic Surgery, 84,685 patients beyond 65 years of age searched out plastic surgery techniques in 2010. Of that number, more than 26,000 had confronted to having undergone lifts, almost 25,000 had cosmetic eyelid surgeries, 6,400 underwent liposuction and more than 5,800 had bosom reduction. Fewer patients likewise decided on face lifts, bosom lifts and bosom enlargements. Those numbers have been on a relentless increment for a long time, as per specialists.plumping up areas such as the cheeks, lips, and under-eye region. These treatments provide a youthful appearance without the need for surgery and have become widely accessible due to their minimal downtime and relatively low cost. In addition to injectables, a variety of skin treatments and therapies have gained popularity for rejuvenation. Laser treatments, such as fractional CO2 lasers or IPL (intense pulsed light), target skin concerns like hyperpigmentation, fine lines, and acne scars by stimulating collagen production and promoting skin renewal. Chemical peels and microneedling are also common methods that help to exfoliate the skin, remove damaged cells, and encourage cell regeneration. These procedures improve skin texture, tone, and elasticity, resulting in a smoother, more youthful appearance.
Genetics of aging is generally concerned with life extension associated with genetic alterations, rather than with accelerated aging diseases leading to reduction in lifespan. The role of genetics in determining life-span is complex and paradoxical. Although the heritability of life-span is relatively minor, some genetic variants significantly modify senescence of mammals and invertebrates, with both positive and negative impacts on age-related diseases and life-spans.Telomeres are protective caps at the ends of chromosomes that prevent them from deteriorating or fusing with other chromosomes. Each time a cell divides, its telomeres shorten, and eventually, the telomeres become too short to protect the chromosomes, leading to cellular senescence or apoptosis (programmed cell death). This process limits the number of times a cell can divide, contributing to the aging of tissues and organs. In this context, telomere shortening is linked to age-related diseases such as heart disease .
Traditional and Regenerative medicine is mainly concentrates on the longevity of life by developing the anti-aging medicine. Customary drug includes restorative parts of conventional information that created over eras inside different social orders before the time of cutting edge prescription. The World Health Organization (WHO) characterizes conventional solution as "the whole of the learning, abilities, and practices in view of the speculations, convictions, and encounters indigenous to various societies, whether logical or not, utilized as a part of the upkeep of wellbeing and also in the avoidance, conclusion, change or treatment of physical and emotional instability.Longevity, or the ability to live a long and healthy life, has been a central focus of medicine throughout history. With advancements in medical science, humans are living longer than ever before, and the field of medicine continues to explore ways to not only extend lifespan but also enhance the quality of life in later years. As the global population ages, the emphasis has shifted from simply treating diseases to promoting healthy aging and preventing the onset of age-related conditions, such as heart disease, diabetes, and neurodegenerative disorders.