Senescence

Senescence is defined as the period when synthetic (anabolic) biochemical process gives way to a degradative (catabolic) process. In general, it is the phenomenon of aging. It is the gradual deterioration of functional characteristics. It is the inevitable fate of all multicellular organisms with germ-soma separation, but it can be delayed. The pattern of Senescence can be Cellular Senescence, Tissue Senescence, Organ Senescence, Organism or Whole plant Senescence.The presence of these dysfunctional cells has also been linked to neurodegenerative diseases like Alzheimer's and Parkinson's, where they exacerbate cognitive decline. Senescence is not only a cellular process but also a broader biological phenomenon with implications for aging and disease. As research continues to uncover the mechanisms behind cellular senescence, it offers new opportunities for interventions that may help slow the aging process, improve health in older adults, and reduce the burden of age-related diseases.In tissues such as the skin, muscles, and blood vessels, senescent cells contribute to the decline in function and the development of age-related conditions. For example, in the skin, the accumulation of senescent cells can lead to wrinkles and reduced elasticity, while in the cardiovascular system, they contribute to arterial stiffness and the increased risk of heart disease

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